Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686692 | 0.80 | GABRA1 (0.39) | — | |
| SCHEMBL8039534 | 0.77 | — | — | |
| SCHEMBL19492085 | 0.73 | THRB (0.32) | THRB | |
| SCHEMBL6969847 | 0.73 | NQO2 (0.47) | MAPTNPC1SMN1; SMN2TP53RAB9A | |
| SCHEMBL9462921 | 0.71 | MAPT (0.41) | MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL29561649 | 0.70 | — | — | |
| SCHEMBL8049797 | 0.69 | HTT (0.35) | MAPTNPC1SMN1; SMN2TP53RAB9A | |
| SCHEMBL9522187 | 0.68 | KDM4E (0.44) | MAPTNPC1SMN1; SMN2TP53RAB9A | |
| SCHEMBL8485908 | 0.66 | PSMB8 (0.42) | MAPTNPC1TP53 | |
| SCHEMBL8054084 | 0.66 | ADRA1D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502473-B1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | NOVARTIS AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| US-5384321-A | Benzothiadiazole compounds | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5260423-A | Fungicide, viricide or bactericide | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |