Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524926 | 0.82 | KDM4E (0.62) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL2293623 | 0.80 | ALDH1A1 (0.63) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL2290042 | 0.80 | HDAC8 (0.63) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL1926964 | 0.77 | MTOR (0.52) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL3673898 | 0.77 | KCNK3 (0.61) | HDAC1HDAC2GRM5F2MEN1 | |
| SCHEMBL29532463 | 0.77 | PARP1 (0.59) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL2093436 | 0.77 | HDAC1 (0.44) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL1259478 | 0.77 | PARP1 (0.59) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL3673834 | 0.76 | ATM (0.58) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL18079795 | 0.76 | CES2 (0.54) | HDAC1HDAC2GRM5F2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |