Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973659 | 0.92 | MEN1 (0.34) | ALDH1A1LMNAIDO1KMT2ACYP3A4 | |
| SCHEMBL7079911 | 0.89 | SLC2A1 (0.34) | ALDH1A1KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7083467 | 0.88 | IDO1 (0.35) | ALDH1A1LMNAIDO1KMT2ARAB9A | |
| SCHEMBL7081085 | 0.88 | RECQL (0.37) | LMNAKMT2ACYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6967430 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAIDO1NPC1KMT2A | |
| SCHEMBL6972366 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAIDO1NPC1KMT2A | |
| SCHEMBL6970549 | 0.85 | IDO1 (0.35) | ALDH1A1IDO1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7081288 | 0.84 | MAPT (0.38) | ALDH1A1LMNAKMT2ARAB9AGAA | |
| SCHEMBL6969546 | 0.84 | IDO1 (0.36) | ALDH1A1IDO1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7085415 | 0.83 | TP53 (0.39) | ALDH1A1LMNAKMT2ACYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |