⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970104 | 1.00 | — | — | |
| SCHEMBL16661958 | 0.77 | — | — | |
| SCHEMBL13004297 | 0.77 | — | — | |
| SCHEMBL20690885 | 0.77 | — | — | |
| SCHEMBL19219854 | 0.77 | CHRNB2 (0.39) | — | |
| SCHEMBL19082518 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL17036665 | 0.77 | KIF11 (0.39) | — | |
| SCHEMBL11396640 | 0.76 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL19091523 | 0.74 | TDP1 (0.44) | — | |
| SCHEMBL16478921 | 0.74 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10307402-B2 | Azabenzimidazole derivatives as agonists of the AMP-activated protein kinase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-06-04 | — | — | US | disclosed |
| US-10189869-B2 | Amino compounds for treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| WO-2019014618-A1 | HETEROCYCLIC INHIBITORS OF ATR KINASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2019-01-17 | — | — | WO | disclosed |
| EP-3245210-B1 | NEW AZABENZIMIDAZOLE DERIVATIVES AS AGONISTS OF THE AMP-ACTIVATED PROTEIN KINASE | BOEHRINGER INGELHEIM INT (DE) | 2018-10-24 | — | — | EP | disclosed |
| US-20180028500-A1 | New Azabenzimidazole Derivatives as Agonists of the AMP-Activated Protein Kinase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| EP-3245210-A1 | NEW AZABENZIMIDAZOLE DERIVATIVES AS AGONISTS OF THE AMP-ACTIVATED PROTEIN KINASE | Boehringer Ingelheim International GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-20170189410-A1 | Amino Compounds for Treatment of Complement Mediated Disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-07-06 | — | — | US | disclosed |
| WO-2017101890-A1 | SPIROKETAL DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION | 上海艾力斯医药科技有限公司 | 2017-06-22 | — | — | WO | disclosed |
| EP-2917185-B1 | SULFOXIMINE SUBSTITUTED QUINAZOLINES FOR PHARMACEUTICAL COMPOSITIONS | EVOTEC INT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| CN-104955332-B | The method of preventing and treating arthropod insect | 住友化学株式会社 | 2017-03-29 | — | — | CN | disclosed |
| US-20090053455-A1 | OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND | MITSUBISHI KAGAKU MEDIA CO., LTD (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090053455-A1 | OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND | MITSUBISHI KAGAKU MEDIA CO., LTD (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1864822-A1 | OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND | Mitsubishi Kagaku Media Corporation, Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070184386-A1 | Optical recording material and optical recording medium | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070184386-A1 | Optical recording material and optical recording medium | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070054219-A1 | Azo-metal chelate dye and optical recording medium | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20070054219-A1 | Azo-metal chelate dye and optical recording medium | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0920415-A1 | SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007700-A1 | SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |