Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147762 | 0.93 | NAAA (0.40) | DGKATDP1MAPTHTR2CPRSS1 | |
| SCHEMBL6973755 | 0.91 | DGKA (0.41) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL6789825 | 0.88 | CYP19A1 (0.45) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL10654547 | 0.88 | ADRA2A (0.46) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL491459 | 0.86 | DGKA (0.47) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL7591037 | 0.86 | CA1 (0.43) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL322130 | 0.86 | DGKA (0.52) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL4285860 | 0.86 | DGKA (0.47) | DGKATDP1ADRA2AADRA1ACYP19A1 | |
| SCHEMBL6785356 | 0.84 | TDP1 (0.40) | DGKATDP1CYP19A1BLMPTPN1 | |
| SCHEMBL16861153 | 0.84 | DGKA (0.55) | DGKATDP1MAPTPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |