Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.77 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acotiamide SCHEMBL30872102 | 0.87 | ACHE (1.00) | ACHEMEN1KMT2ANPC1RAB9A | |
| Acotiamide SCHEMBL28293346 | 0.87 | ACHE (1.00) | ACHEMEN1KMT2ANPC1RAB9A | |
| Acotiamide SCHEMBL1043131 | 0.87 | ACHE (1.00) | ACHEMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6963780 | 0.86 | ACHE (0.77) | ACHEMEN1KMT2ANPC1RAB9A | |
| Acotiamide SCHEMBL6968566 | 0.86 | ACHE (1.00) | ACHEMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6973893 | 0.85 | ACHE (0.91) | ACHEMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6975742 | 0.85 | ACHE (0.91) | ACHEMEN1KMT2ANPC1RAB9A | |
| Acotiamide SCHEMBL27938245 | 0.85 | ACHE (0.98) | ACHEMEN1KMT2ANPC1RAB9A | |
| Acotiamide SCHEMBL29362154 | 0.85 | ACHE (0.98) | ACHEMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6968413 | 0.84 | ACHE (0.86) | ACHEMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |