Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179609 | 0.76 | PI4KA (0.37) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22474028 | 0.76 | PI4KA (0.37) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22474026 | 0.73 | MEN1 (0.37) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL32680234 | 0.73 | ADORA2A (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22735080 | 0.72 | PI4KA (0.34) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6969752 | 0.72 | PI4KA (0.34) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Hexazole SCHEMBL2111420 | 0.72 | ALDH1A1 (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL23638593 | 0.69 | ALDH1A1 (0.33) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21783961 | 0.69 | CCNT1 (0.39) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL12949685 | 0.67 | VCP (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |