Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 2/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | TXN | P10599 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969752 | 0.77 | PI4KA (0.34) | POLBALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12949444 | 0.77 | POLB (0.49) | VCPMAPK1MAOAMAOBPOLB | |
| SCHEMBL11514025 | 0.67 | ALDH1A1 (0.49) | VCPMAPK1POLBALDH1A1MAPT | |
| SCHEMBL11510738 | 0.67 | MAOA (0.36) | VCPMAPK1MAOAMAOBPOLB | |
| SCHEMBL11511317 | 0.67 | VCP (0.45) | VCPMAPK1MAOAMAOBPOLB | |
| SCHEMBL6970733 | 0.67 | PI4KA (0.37) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22474028 | 0.67 | PI4KA (0.37) | ALDH1A1MAPTPI4KAPI4K2BPI4K2A | |
| SCHEMBL8179609 | 0.67 | PI4KA (0.37) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22474026 | 0.64 | MEN1 (0.37) | ALDH1A1SMN1; SMN2PI4KAPI4K2BPI4K2A | |
| SCHEMBL32680234 | 0.64 | ADORA2A (0.35) | ALDH1A1HPGDPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |