Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964956 | 0.80 | L3MBTL1 (0.47) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6970481 | 0.79 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6966662 | 0.71 | NPSR1 (0.44) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL8292304 | 0.63 | KAT6A (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14495384 | 0.60 | KDM4C (0.62) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL2453964 | 0.60 | SMN1; SMN2 (0.66) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL20037334 | 0.59 | PDE4D (0.56) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1379363 | 0.59 | NPC1 (0.52) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL20037217 | 0.59 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL7501911 | 0.58 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |