Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966662 | 0.85 | NPSR1 (0.44) | MEN1KMT2AGRM5NPC1RAB9A | |
| SCHEMBL6970818 | 0.79 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6965184 | 0.78 | MAPT (0.40) | MEN1KMT2ANPC1UBE2MDCUN1D1 | |
| SCHEMBL6971557 | 0.74 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1LMNATSHR | |
| SCHEMBL6964978 | 0.73 | NPC1 (0.42) | GRM5NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6972135 | 0.73 | MEN1 (0.47) | MEN1KMT2APLK1ALDH1A1LMNA | |
| SCHEMBL6964956 | 0.72 | L3MBTL1 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6970219 | 0.70 | MEP1A (0.41) | MEN1KMT2ANPC1NR3C1MEP1A | |
| SCHEMBL6973143 | 0.69 | MAPK1 (0.42) | NPC1RAB9ANR3C1MEP1AMEP1B | |
| SCHEMBL6971363 | 0.69 | AR (0.39) | MEN1KMT2AMEP1AMEP1BAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |