Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226210 | 0.85 | NR1H4 (0.59) | ALDH1A1HPGDMAPK1POLBCYP2C19 | |
| SCHEMBL3054871 | 0.85 | NR1H4 (0.59) | ALDH1A1HPGDMAPK1POLBCYP2C19 | |
| SCHEMBL7055476 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL28030687 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL1644965 | 0.82 | MAPK1 (0.59) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL14592349 | 0.82 | TSHR (0.54) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL10650419 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL6966015 | 0.81 | KDM4E (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2POLB | |
| SCHEMBL30168125 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL3150784 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |