Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275740 | 0.84 | L3MBTL1 (0.46) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL1964864 | 0.84 | PTGS2 (0.60) | PTGS2CXCL8NR1H4PTGS1AKR1B10 | |
| SCHEMBL22316652 | 0.82 | KMT2A (0.45) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL3743443 | 0.82 | KDM4E (0.43) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL24260205 | 0.81 | L3MBTL1 (0.46) | KDM4EPOLBATMPTGS2CXCL8 | |
| Ammonia Solution, Strong SCHEMBL28139473 | 0.81 | KDM4E (0.42) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL11989069 | 0.81 | KDM4E (0.50) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL6970823 | 0.81 | ALDH1A1 (0.53) | KDM4EPOLBALDH1A1SMN1; SMN2NR1H4 | |
| SCHEMBL19574717 | 0.79 | PTGS2 (0.41) | KDM4EPOLBATMPTGS2CXCL8 | |
| SCHEMBL18294035 | 0.79 | MAPT (0.44) | KDM4EPOLBATMPTGS2CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |