Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976446 | 0.86 | PTGS2 (0.69) | PTGS2PTGS1MEN1LMNAKMT2A | |
| SCHEMBL6980615 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1MEN1KMT2ACA12 | |
| SCHEMBL6976803 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1MAOAMAOBCA12 | |
| SCHEMBL6978176 | 0.82 | KDM4E (0.52) | PTGS2PTGS1MEN1LMNAKMT2A | |
| SCHEMBL6975423 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL6981287 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1MEN1LMNAKMT2A | |
| SCHEMBL6978811 | 0.82 | PTGS1 (0.59) | PTGS2PTGS1MEN1LMNAKMT2A | |
| SCHEMBL6979214 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1MEN1LMNAKMT2A | |
| SCHEMBL6977374 | 0.80 | GABRP (0.41) | PTGS2MEN1LMNAKMT2AGABRP | |
| SCHEMBL6975328 | 0.79 | PTGS2 (0.66) | PTGS2PTGS1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |