Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.41 |
| ▸ | GABRD | O14764 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.41 |
| ▸ | GABRE | P78334 | 4/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694389 | 0.81 | RXFP1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6970840 | 0.80 | PTGS2 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6983326 | 0.78 | MAPK14 (0.49) | ACHEBACE1MAPK14PTGS2 | |
| SCHEMBL6982162 | 0.74 | PTGS2 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6980093 | 0.73 | PTGS2 (0.43) | ACHEBACE1KDM4EKMT2AMEN1 | |
| SCHEMBL6981848 | 0.72 | MAPK14 (0.40) | ACHEBACE1KDM4EKMT2AMEN1 | |
| SCHEMBL6976542 | 0.68 | PTGS2 (0.69) | MAPK14PTGS2 | |
| SCHEMBL6978328 | 0.68 | PTGS2 (0.54) | ACHEBACE1PTGS2 | |
| SCHEMBL7678962 | 0.67 | MEN1 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30991592 | 0.67 | KMT2A (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |