Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942553 | 0.85 | PKM (0.50) | PKMCYP11B1CYP11B2ALDH1A1NR4A1 | |
| SCHEMBL1267736 | 0.82 | KDM4E (0.57) | ALDH1A1MAPTHTTPOLBCA5A | |
| SCHEMBL2369495 | 0.81 | S1PR3 (0.51) | CYP11B1CYP11B2ALDH1A1MEN1KMT2A | |
| SCHEMBL30737737 | 0.81 | S1PR3 (0.51) | CYP11B1CYP11B2ALDH1A1MEN1KMT2A | |
| SCHEMBL2427132 | 0.80 | CA1 (0.62) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL32665335 | 0.80 | ERN1 (0.42) | ALDH1A1MAPTHPGD | |
| SCHEMBL5899647 | 0.79 | S1PR3 (0.52) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL842203 | 0.79 | CYP11B1 (0.42) | PKMCYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL1953476 | 0.79 | CYP11B2 (0.60) | CYP11B1CYP11B2MAPT | |
| SCHEMBL22212824 | 0.78 | HDAC3 (0.45) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802550-B1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INST NAT SANTE RECH MED (FR) | 2023-12-27 | — | — | EP | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| CN-116217603-A | New compounds | 国家医疗保健研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-112236433-B | Novel compounds | 国家医疗保健研究所 | 2023-04-04 | — | — | CN | disclosed |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2022-08-25 | — | — | US | disclosed |
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-07 | — | — | US | disclosed |
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-07 | — | — | US | disclosed |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2021-08-19 | — | — | US | disclosed |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2021-08-19 | — | — | US | disclosed |
| EP-3802550-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2021-04-14 | — | — | EP | disclosed |
| CN-112236433-A | Novel compounds | 国家医疗保健研究所 | 2021-01-15 | — | — | CN | disclosed |
| WO-2019234075-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019234075-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |
| US-6649636-B1 | Cyclooxygenase inhibitors | PFIZER INC. | 2003-11-18 | — | — | US | disclosed |
| EP-1104759-B1 | Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1104759-A1 | Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK5 | PKM 772/4885CYP11B1 1607/4885CYP11B2 1859/4885 |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | PKM 885/4885CYP11B1 2253/4885CYP11B2 2458/4885 |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | PKM 886/4885CYP11B1 2267/4885CYP11B2 2464/4885 |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK2 | PKM 850/4885CYP11B1 1487/4885CYP11B2 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.