Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.54 |
| ▸ | CNR1 | P21554 | 5/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6968039 | 0.99 | CNR2 (0.53) | CNR2CNR1ACHEPLA2G2AABHD6 | |
| SCHEMBL6971046 | 0.90 | CNR1 (0.45) | CNR2CNR1ACHEPLA2G2AABHD6 | |
| SCHEMBL6974448 | 0.85 | CNR1 (0.48) | CNR2CNR1ACHEPLA2G2AKDM4E | |
| SCHEMBL6973326 | 0.80 | CNR2 (0.58) | CNR2CNR1ACHEPLA2G2AABHD6 | |
| SCHEMBL6979571 | 0.78 | CNR2 (0.56) | CNR2CNR1ACHEPLA2G2AABHD6 | |
| SCHEMBL6968297 | 0.77 | CNR2 (0.49) | CNR2CNR1ACHEPLA2G2AABHD6 | |
| SCHEMBL6978209 | 0.76 | CNR1 (0.49) | CNR2CNR1ACHEKDM4EGUCY1B2 | |
| SCHEMBL6978241 | 0.74 | CNR2 (0.49) | CNR2CNR1ACHEPLA2G2APTGER4 | |
| SCHEMBL6975679 | 0.74 | CNR2 (0.49) | CNR2CNR1ACHEPLA2G2AALDH1A1 | |
| SCHEMBL6975035 | 0.73 | PLA2G2A (0.43) | CNR2CNR1ACHEPLA2G2AABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |