Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | FLT1 | P17948 | 5/20 | 0.56 |
| ▸ | FLT4 | P35916 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419345 | 0.83 | ALDH1A1 (0.77) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL6790469 | 0.82 | KDM4E (0.69) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL393739 | 0.82 | KDM4E (0.69) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL180845 | 0.81 | SMN1; SMN2 (0.71) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL1127878 | 0.80 | KDM4E (1.00) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL4154496 | 0.80 | KDM4E (0.67) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL29833777 | 0.80 | KDM4E (0.67) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21381943 | 0.78 | KDM4E (0.96) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL9782403 | 0.77 | KDM4E (0.62) | KDM4EMAPTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL1514676 | 0.77 | KDM4E (0.68) | KDM4EMAPTPOLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |