Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185351 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL195020 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL8065539 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL5732135 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL5667181 | 0.83 | ALDH1A1 (0.68) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL107060 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL19998346 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL111279 | 0.83 | TSHR (1.00) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL322161 | 0.81 | TSHR (0.65) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 | |
| SCHEMBL1303476 | 0.81 | TSHR (0.95) | SMN1; SMN2TSHRCASP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551360-B2 | Pyrazoline-3,5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | VIDAL LAURENT (FR) | 2003-04-22 | — | — | US | claimed |
| US-6340372-B1 | Compositions for dyeing keratin fibers containing S-oxide-thiazolo-azoles and/or S,S-dioxide-thiazolo-azoles; their use for dyeing as couplers, method of dyeing | L'OREAL S.A. (FR) | 2002-01-22 | — | — | US | claimed |
| US-6139589-A | HAIR DYES | L'OREAL S.A. (FR) | 2000-10-31 | — | — | US | claimed |
| US-6063136-A | Compositions containing pyrrolo-oxazole couplers for dyeing keratin fibers and dyeing methods | L'OREAL S.A. (FR) | 2000-05-16 | — | — | US | claimed |
| US-5116990-A | MAGENTA DYE-FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-26 | — | — | US | claimed |
| EP-0170164-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-05 | — | — | EP | claimed |
| EP-0249999-A2 | Triazolyl ethyl ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | claimed |
| US-H122-H | PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1986-09-02 | — | — | US | claimed |
| EP-0170164-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-02-05 | — | — | EP | claimed |
| US-20130210786-A1 | TREATMENT OF L-DOPA, DOPAMINE AGONIST AND/OR DOPAMINE ENHANCER INDUCED DISORDERS | PHYTOPHARM PLC (GB) | 2013-08-15 | — | — | US | disclosed |
| EP-2595621-A1 | TREATMENT OF L-DOPA, DOPAMINE AGONIST AND/OR DOPAMINE ENHANCER INDUCED DISORDERS | Phytopharm PLC (GB) | 2013-05-29 | — | — | EP | disclosed |
| EP-2479183-A2 | Polymorphs of sarsasapogenin | Phytopharm PLC (GB) | 2012-07-25 | — | — | EP | disclosed |
| US-20120034193-A1 | TREATMENT OF NEUROTROPHIC FACTOR MEDIATED DISORDERS | PHYTOPHARM PLC (GB) | 2012-02-09 | — | — | US | disclosed |
| WO-2012010896-A1 | TREATMENT OF L-DOPA, DOPAMINE AGONIST AND/OR DOPAMINE ENHANCER INDUCED DISORDERS | PHYTOPHARM PLC (GB) | 2012-01-26 | — | — | WO | disclosed |
| EP-0119860-A2 | Pyrazolo magenta couplers used in silver halide photography | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-26 | — | — | EP | disclosed |
| EP-0087596-A1 | Process for the preparation of 5-substituted 1-chloro-3,3-dimethyl-pentan-2-ones | BAYER AG (DE) | 1983-09-07 | — | — | EP | disclosed |
| US-4239851-A | DISSOLVING AN OIL SOLUBLE ADDITIVE IN AN EPOXY COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-16 | — | — | US | disclosed |
| US-4101464-A | Process for preparing foamed solids using two or more azo compounds | PENNWALT CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4029615-A | AZO COMPOUNDS | PENNWALT CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-3993609-A | ACID SENSITIVE AZO PROMOTERS | PENNWALT CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034193-A1 | TREATMENT OF NEUROTROPHIC FACTOR MEDIATED DISORDERS | BDNF, NGF, GFRA1 | SMN1; SMN2 80/4885TSHR 2367/4885CASP1 547/4885 |
| US-20130210786-A1 | TREATMENT OF L-DOPA, DOPAMINE AGONIST AND/OR DOPAMINE ENHANCER INDUCED DISORDERS | SNCA, DBH, COMT | SMN1; SMN2 1238/4885TSHR 1166/4885CASP1 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.