SCHEMBL6971078

SCHEMBL6971078

Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c([N+](=O)[O-])c2F)c1=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965117 0.89 GRIN2D (0.32) ALDH1A1TSHRMEN1KMT2A
SCHEMBL7655980 0.89 MAPT (0.32) ALDH1A1TSHRMEN1KMT2A
SCHEMBL5382406 0.87 GRIN2D (0.32) MEN1KMT2A
SCHEMBL7559209 0.85 GRIN2D (0.38) MEN1KMT2A
SCHEMBL7684644 0.78 ALDH1A1 (0.34) ALDH1A1TSHRKMT2A
SCHEMBL5398338 0.78 GPR35 (0.31)
SCHEMBL6970318 0.78 GRM4 (0.32)
SCHEMBL7661919 0.77
SCHEMBL6792340 0.77 COMT (0.30)
SCHEMBL6678212 0.77 GRIN2D (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624119-B1 Herbicidally active uracil compounds which allow better targeted control of undesirable plants than the known uracil compounds BASF AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
EP-1131319-B1 3- BENZ(OX/THI)AZOL-7-YL -1H-PYRIMIDINE-2,4-DIONES BASF AG (DE) 2003-09-03 EP disclosed
US-6352958-B1 PRE- AND POST-EMERGENCE HERBICIDES FMC CORPORATION 2002-03-05 US disclosed
US-6077812-A 4-OR 7-(2,6-DI(OXO),3-SUBSTITUTED, 4-TRIFLUOROMETHYL-1,2,3, 6-TETRAHYDROPYRIMIDIN-1-YL)BENZIMIDAZOLES; CONTROLLING WEEDS FMC CORPORATION (US) 2000-06-20 US disclosed
EP-0968207-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 2000-01-05 EP disclosed
WO-1998038188-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 1998-09-03 WO disclosed