SCHEMBL6792340

SCHEMBL6792340

Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c(O)c2N)c1=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970724 0.91 COMT (0.30) COMT
SCHEMBL7661919 0.89
SCHEMBL5393287 0.87 L3MBTL1 (0.30)
SCHEMBL7668746 0.86
SCHEMBL7905033 0.86 GRM4 (0.32)
SCHEMBL5391301 0.84 BCAT2 (0.32)
SCHEMBL7669350 0.83 GRM4 (0.30)
SCHEMBL7655980 0.82 MAPT (0.32)
SCHEMBL5382406 0.82 GRIN2D (0.32)
SCHEMBL7657861 0.81 BCAT2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029734-A1 Fused-benzene derivatives useful as herbicides ISHIHARA SANGYO KAISHA, LTD. 2004-02-12 US disclosed
US-6573218-B1 Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-03 US disclosed
EP-1111993-A4 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 2002-12-04 EP disclosed
US-6352958-B1 PRE- AND POST-EMERGENCE HERBICIDES FMC CORPORATION 2002-03-05 US disclosed
EP-1111993-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-07-04 EP disclosed
US-6077812-A 4-OR 7-(2,6-DI(OXO),3-SUBSTITUTED, 4-TRIFLUOROMETHYL-1,2,3, 6-TETRAHYDROPYRIMIDIN-1-YL)BENZIMIDAZOLES; CONTROLLING WEEDS FMC CORPORATION (US) 2000-06-20 US disclosed
WO-2000013508-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-03-16 WO disclosed
EP-0968207-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 2000-01-05 EP disclosed
WO-1998038188-A1 CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES FMC CORPORATION (US) 1998-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029734-A1 Fused-benzene derivatives useful as herbicides DDT, NQO2, DHRS9 COMT 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.