Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 5/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968646 | 0.90 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6432948 | 0.86 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6968614 | 0.79 | MMP2 (0.64) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6959958 | 0.79 | MMP2 (0.60) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6973071 | 0.78 | DRD2 (0.38) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435284 | 0.77 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6968340 | 0.77 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434450 | 0.76 | MMP2 (0.56) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6437634 | 0.75 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6436938 | 0.74 | MMP2 (0.55) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |