Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 15/20 | 0.46 |
| ▸ | HTR1B | P28222 | 15/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010593 | 0.85 | HTR1D (0.61) | HTR1DHTR1B | |
| SCHEMBL7006155 | 0.82 | HTR1D (0.63) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL7006151 | 0.82 | HTR1D (0.63) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL7878674 | 0.81 | HTR6 (0.37) | SLC6A4HTR6 | |
| SCHEMBL7006006 | 0.80 | SLC6A4 (0.54) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL6971173 | 0.77 | SLC6A4 (0.60) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL7011873 | 0.77 | HTR1B (0.62) | HTR1DHTR1B | |
| SCHEMBL7005968 | 0.77 | HTR1B (0.62) | HTR1DHTR1B | |
| SCHEMBL7010803 | 0.77 | HTR1B (0.62) | HTR1DHTR1B | |
| SCHEMBL7008355 | 0.77 | HTR1B (0.62) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | claimed |
| EP-1098896-A1 | 5-BICYCLOINDOLE COMPOUNDS | NPS Allelix Corp. (CA) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004019-A1 | 5-BICYCLOINDOLE COMPOUNDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-01-27 | — | — | WO | claimed |
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |
| EP-1098896-A1 | 5-BICYCLOINDOLE COMPOUNDS | NPS Allelix Corp. (CA) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004019-A1 | 5-BICYCLOINDOLE COMPOUNDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-01-27 | — | — | WO | disclosed |