Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 11/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR1F | P30939 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894091 | 0.92 | SLC6A4 (0.49) | SLC6A4HTR6HTR1BHTR1AHTR2C | |
| SCHEMBL8686768 | 0.79 | HTR1D (0.64) | SLC6A4HTR6HTR1BHTR1D | |
| SCHEMBL8894085 | 0.78 | HTR1D (0.59) | HTR1BHTR1DBRD4 | |
| SCHEMBL8903222 | 0.78 | HTR1D (0.62) | HTR1BHTR1DBRD4 | |
| SCHEMBL6968677 | 0.77 | SLC6A4 (0.70) | SLC6A4HTR6HTR1BHTR1AHTR2C | |
| SCHEMBL8506913 | 0.77 | SLC6A4 (0.70) | SLC6A4HTR6HTR1BHTR1AHTR2C | |
| SCHEMBL6971173 | 0.77 | SLC6A4 (0.60) | SLC6A4HTR6HTR1BHTR1D | |
| SCHEMBL8903373 | 0.76 | HTR1D (0.62) | SLC6A4HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8506286 | 0.75 | SLC6A4 (0.67) | SLC6A4HTR6HTR1BHTR1AHTR1D | |
| SCHEMBL8480264 | 0.74 | SLC6A4 (0.80) | SLC6A4HTR6HTR1BHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |