Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973501 | 0.85 | ADRB2 (0.55) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL23681041 | 0.83 | ADRB2 (0.54) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL28306812 | 0.81 | CA12 (0.61) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL1365179 | 0.81 | CA12 (0.61) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL6230747 | 0.81 | SNCA (0.54) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL10987144 | 0.80 | GSK3B (0.55) | TDP1KMT2AGSK3BALDH1A1MEN1 | |
| SCHEMBL10941602 | 0.79 | TSHR (0.64) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL24112443 | 0.79 | TDP1 (0.65) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL6965607 | 0.79 | CA2 (0.55) | ADRB2ADRB1ADRB3TDP1L3MBTL1 | |
| SCHEMBL7649941 | 0.78 | CA2 (0.59) | ADRB2ADRB1ADRB3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |