Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649941 | 0.83 | CA2 (0.59) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL247746 | 0.81 | CA2 (0.57) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL14223454 | 0.79 | CA2 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL7393 | 0.79 | CA1 (0.57) | CA2CA1GSK3BALDH1A1MAPT | |
| SCHEMBL23037551 | 0.79 | CA2 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL8840293 | 0.79 | CA1 (0.50) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL6971337 | 0.79 | ADRB2 (0.52) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL8496209 | 0.78 | ALDH1A1 (0.58) | CA2CA1GSK3BPARP15PARP10 | |
| Charcoal, Activated SCHEMBL31430427 | 0.78 | CA1 (0.55) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL10973501 | 0.78 | ADRB2 (0.55) | CA2CA1GSK3BPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |