Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669365 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL4011637 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL1451915 | 0.79 | MAOA (0.38) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL11148751 | 0.74 | L3MBTL1 (0.36) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL6965981 | 0.73 | MEN1 (0.31) | ALDH1A1MEN1KMT2AARPOLB | |
| SCHEMBL11461774 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL408050 | 0.71 | TSHR (0.33) | KDM4EALDH1A1MAOAMAOBCYP1A2 | |
| SCHEMBL5218112 | 0.70 | SIRT1 (0.38) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL1691711 | 0.70 | PDE7A (0.39) | KDM4EALDH1A1MAPTHPGDMAOA | |
| SCHEMBL9685487 | 0.70 | MAOA (0.34) | KDM4EALDH1A1MAPTHPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |