Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046450 | 0.73 | ALDH1A1 (0.39) | L3MBTL1MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL2041393 | 0.70 | — | — | |
| SCHEMBL10406683 | 0.69 | CYP2A6 (0.47) | L3MBTL1MAPK1ALDH1A1HPGDESR2 | |
| SCHEMBL6950450 | 0.69 | CYP2A6 (0.43) | MAPK1ALDH1A1CYP1A2HPGDCYP2A6 | |
| SCHEMBL151224 | 0.69 | ESR2 (0.67) | MAOAMAOBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3139383 | 0.68 | CYP2A6 (0.50) | L3MBTL1MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL5664674 | 0.67 | L3MBTL1 (0.39) | L3MBTL1MAPK1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL223 | 0.66 | ESR2 (0.69) | MAOAMAOBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11840754 | 0.66 | ALDH1A1 (0.55) | L3MBTL1MAPK1MAOAMAOBALDH1A1 | |
| SCHEMBL29662886 | 0.66 | ESR2 (0.69) | MAOAMAOBALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |