Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977148 | 1.00 | NOS1 (0.41) | NOS1NOS2GBA1CTSD | |
| SCHEMBL6964864 | 1.00 | NOS1 (0.41) | NOS1NOS2GBA1CTSD | |
| Hydrochloric Acid SCHEMBL8051182 | 0.98 | NOS1 (0.43) | NOS1NOS2GBA1CTSD | |
| SCHEMBL6976101 | 0.79 | CTSD (0.49) | CTSD | |
| SCHEMBL6968377 | 0.79 | CTSD (0.49) | CTSD | |
| SCHEMBL6976103 | 0.79 | CTSD (0.49) | CTSD | |
| SCHEMBL6978059 | 0.77 | NOS1 (0.44) | NOS1NOS2GBA1 | |
| SCHEMBL6980069 | 0.77 | NOS1 (0.44) | NOS1NOS2GBA1 | |
| SCHEMBL6967461 | 0.77 | NOS1 (0.44) | NOS1NOS2GBA1 | |
| SCHEMBL6977437 | 0.75 | MAOA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |