Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 3/20 | 0.38 |
| ▸ | PRKCB | P05771 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | PRKCH | P24723 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 3/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973974 | 0.96 | LMNA (0.40) | LMNASMN1; SMN2HTTHTR6PRKD3 | |
| SCHEMBL6969044 | 0.80 | KDM4E (0.36) | LMNASMN1; SMN2HTTCYP1A2GAA | |
| SCHEMBL6963410 | 0.79 | KDM4E (0.36) | LMNASMN1; SMN2HTTCYP1A2GAA | |
| SCHEMBL6972930 | 0.78 | PRKD3 (0.41) | LMNASMN1; SMN2HTTHTR6PRKD3 | |
| SCHEMBL6967350 | 0.76 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2HTTHTR6PRKD3 | |
| SCHEMBL6970886 | 0.74 | PRKD3 (0.43) | LMNASMN1; SMN2HTTHTR6PRKD3 | |
| SCHEMBL6965038 | 0.73 | CYP3A4 (0.44) | LMNASMN1; SMN2HTTHTR6PRKD3 | |
| SCHEMBL6966488 | 0.73 | MEN1 (0.44) | LMNASMN1; SMN2PRKD3PRKCGPRKCB | |
| Sulfuric Acid SCHEMBL6973792 | 0.72 | PRKD3 (0.41) | LMNASMN1; SMN2HTTPRKD3PRKCG | |
| SCHEMBL6958223 | 0.71 | P2RX7 (0.42) | LMNASMN1; SMN2HTTHTR6PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855391-B1 | NOVEL ISOQUINOLINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-5959107-A | Isoquinoline derivatives | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0855391-A1 | NOVEL ISOQUINOLINE DERIVATIVES | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |