Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020020 | 0.82 | BUB1 (0.34) | LMNASMN1; SMN2BUB1RXFP1MAPT | |
| SCHEMBL17266363 | 0.82 | LMNA (0.31) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL6178552 | 0.79 | KMT2A (0.35) | LMNABUB1CYP3A4MAPTAPEX1 | |
| SCHEMBL23012609 | 0.78 | NOS2 (0.34) | — | |
| SCHEMBL17371795 | 0.77 | PNMT (0.46) | — | |
| SCHEMBL844396 | 0.77 | LMNA (0.31) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL30673110 | 0.77 | RECQL (0.42) | LMNASMN1; SMN2BUB1CYP3A4MAPT | |
| SCHEMBL10349426 | 0.77 | LMNA (0.31) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL844264 | 0.77 | RECQL (0.42) | LMNASMN1; SMN2BUB1CYP3A4MAPT | |
| SCHEMBL7988273 | 0.77 | BUB1 (0.35) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |