SCHEMBL69716

SCHEMBL69716

O=C(O)c1cccc2c1-c1c(C(=O)O)cccc1-2

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
MAPT P10636 3/20 0.69
LMNA P02545 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.63
HNF4A P41235 1/20 0.59
HSD17B10 Q99714 2/20 0.58
MYC P01106 1/20 0.57
ALOX15 P16050 1/20 0.57
POLB P06746 1/20 0.55
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
GAA P10253 1/20 0.49
RAB9A P51151 1/20 0.49
GFER P55789 1/20 0.49
KMT2A Q03164 1/20 0.49
LIG1 P18858 1/20 0.48
TSHR P16473 1/20 0.48
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70265 0.90 ALDH1A1 (0.63) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL3616574 0.88 ALDH1A1 (0.74) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL5866519 0.88 ALDH1A1 (0.81) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL31278212 0.88 ALDH1A1 (0.74) ALDH1A1MAPTLMNAL3MBTL1HNF4A
Hydrochloric Acid SCHEMBL2402126 0.86 ALDH1A1 (0.71) ALDH1A1MAPTLMNAL3MBTL1HNF4A
Hydrochloric Acid SCHEMBL15366836 0.86 ALDH1A1 (0.71) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL5089936 0.86 ALDH1A1 (0.66) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL203394 0.86 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL160565 0.83 MYC (0.68) ALDH1A1MAPTLMNAL3MBTL1HNF4A
SCHEMBL31540338 0.83 MYC (0.68) ALDH1A1MAPTLMNAL3MBTL1HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885MAPT 1923/4885LMNA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.