SCHEMBL5089936

SCHEMBL5089936

O=C(O)c1ccccc1-c1cccc(C(=O)O)c1-c1ccccc1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
LMNA P02545 2/20 0.66
MYC P01106 1/20 0.66
MAPT P10636 1/20 0.66
L3MBTL1 Q9Y468 2/20 0.60
HNF4A P41235 1/20 0.57
ALOX15 P16050 1/20 0.54
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX12 P18054 1/20 0.53
GAA P10253 2/20 0.51
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
GFER P55789 1/20 0.51
KMT2A Q03164 1/20 0.51
FOLH1 Q04609 2/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 1/20 0.49
SOS1 Q07889 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160565 0.93 MYC (0.68) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL31540338 0.93 MYC (0.68) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL3616574 0.89 ALDH1A1 (0.74) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL31278212 0.89 ALDH1A1 (0.74) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL15569044 0.88 HNF4A (0.69) ALDH1A1LMNAMYCMAPTL3MBTL1
Hydrochloric Acid SCHEMBL2402126 0.87 ALDH1A1 (0.71) ALDH1A1LMNAMYCMAPTL3MBTL1
Hydrochloric Acid SCHEMBL15366836 0.87 ALDH1A1 (0.71) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL11061912 0.86 MYC (0.64) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL70265 0.86 ALDH1A1 (0.63) ALDH1A1LMNAMYCMAPTL3MBTL1
SCHEMBL11217790 0.86 MYC (0.69) ALDH1A1LMNAMYCMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390924-B2 Terphenyl derivatives, preparation thereof, compositions containing same SANOFI-AVENTIS (FR) 2008-06-24 US claimed
EP-1497274-B1 TERPHENYL DERIVATIVES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME SANOFI AVENTIS (FR) 2006-09-13 EP claimed
US-20060167049-A1 Terphenly derivatives, preparation thereof, compositions containing same SANOFI-AVENTIS (FR) 2006-07-27 US claimed
WO-2023221455-A1 POLYMER-MOF COMPOSITE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 广东美的白色家电技术创新中心有限公司 2023-11-23 WO disclosed
US-7390924-B2 Terphenyl derivatives, preparation thereof, compositions containing same SANOFI-AVENTIS (FR) 2008-06-24 US disclosed
US-20060167049-A1 Terphenly derivatives, preparation thereof, compositions containing same SANOFI-AVENTIS (FR) 2006-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167049-A1 Terphenly derivatives, preparation thereof, compositions containing same CNR1, CNR2, TRPV1 ALDH1A1 2652/4885LMNA 3680/4885MYC 4166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.