Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HNF4A | P41235 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MYC | P01106 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278212 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| Hydrochloric Acid SCHEMBL15366836 | 0.98 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| Hydrochloric Acid SCHEMBL2402126 | 0.98 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL5089936 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL69716 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL70265 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL87757 | 0.85 | HNF4A (0.69) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL581124 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL600330 | 0.85 | ALDH1A1 (0.85) | ALDH1A1MAPTLMNAL3MBTL1HNF4A | |
| SCHEMBL31276140 | 0.85 | ALDH1A1 (0.85) | ALDH1A1MAPTLMNAL3MBTL1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764566-A | HIGH STRENGTH | ALLIED-SIGNAL INC. (US) | 1988-08-16 | — | — | US | claimed |
| CN-110386934-A | Compound and the organic electroluminescent device for utilizing it | 株式会社斗山 | 2019-10-29 | — | — | CN | disclosed |
| CN-107522703-A | Organic compound and organic electro-optic device and display device for photoelectric device | 三星SDI株式会社 | 2017-12-29 | — | — | CN | disclosed |
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2010-03-25 | — | — | US | disclosed |
| CN-101649043-A | Polyester for producing fiber, and fiber and non-woven fabric using the same | SUMITOMO CHEMICAL CO JP | 2010-02-17 | — | — | CN | disclosed |
| EP-2089395-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UnibioScreen S.A. (BE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008043846-A2 | NEW ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | UNIBIOSCREEN SA (BE) | 2008-04-17 | — | — | WO | disclosed |
| US-5420348-A | Enzyme inhibitors | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0447116-B1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5258405-A | Acetyl coenzyme A cholesterol acetyltransferase inhibitors for cardiovascular disorders and atherosclerosis and antilipemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0447116-A1 | Urea derivatives, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4764566-A | HIGH STRENGTH | ALLIED-SIGNAL INC. (US) | 1988-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076005-A1 | ISOCARBOSTYRIL ALKALOID DERIVATIVES HAVING ANTI-PROLIFERATIVE AND ANTI-MIGRATORY ACTIVITIES | MIF, IMPDH1, IMPDH2 | ALDH1A1 445/4885MAPT 680/4885LMNA 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.