Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MB | P02144 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971648 | 0.78 | HTT (0.64) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAPRT | |
| SCHEMBL6966248 | 0.75 | BCAT2 (0.56) | HTTKMT2AMEN1RAB9AKDM4E | |
| SCHEMBL17267019 | 0.74 | HIF1A (0.48) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL21719735 | 0.74 | KDM1A (0.47) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL4293848 | 0.74 | NPC1 (0.52) | SMN1; SMN2ALDH1A1HTTL3MBTL1NAPRT | |
| SCHEMBL25043757 | 0.73 | IDO1 (0.42) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL4281610 | 0.70 | EGFR (0.54) | SMN1; SMN2HTTL3MBTL1NAPRTHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL29505602 | 0.69 | L3MBTL1 (0.53) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL23570884 | 0.69 | HIF1A (0.50) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL23547595 | 0.69 | HIF1A (0.44) | HIF1ASMN1; SMN2ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |