Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966254 | 0.82 | EGFR (0.70) | BCAT2EGFRFGFR1KDRJAK2 | |
| SCHEMBL4293257 | 0.81 | EGFR (0.70) | BCAT2EGFRFGFR1KDRNAMPT | |
| SCHEMBL4285419 | 0.78 | NPC1 (0.69) | BCAT2EGFRFGFR1KDRJAK2 | |
| SCHEMBL4283175 | 0.77 | NAMPT (0.69) | NAMPTTAS2R8MEN1KMT2A | |
| SCHEMBL6971646 | 0.75 | HIF1A (0.41) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4286765 | 0.75 | CLK2 (0.54) | BCAT2EGFRFGFR1KDRNAMPT | |
| SCHEMBL4285528 | 0.75 | NAMPT (0.65) | NAMPTRAB9ATAS2R8 | |
| SCHEMBL4968277 | 0.74 | NAMPT (0.61) | EGFRFGFR1KDRJAK2TYK2 | |
| SCHEMBL24202631 | 0.73 | SIRT1 (0.83) | JAK2TYK2PTPN1KCNK3KCNK9 | |
| N-Phenylbenzamide SCHEMBL31966 | 0.73 | SIRT1 (0.83) | JAK2TYK2PTPN1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |