Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200302 | 0.86 | LMNA (0.52) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL4415483 | 0.85 | LMNA (0.58) | HDAC1HDAC8HDAC6LMNAGAA | |
| Hydrochloric Acid SCHEMBL1374005 | 0.84 | LMNA (0.57) | HDAC1HDAC8HDAC6LMNAGAA | |
| SCHEMBL10029593 | 0.79 | LMNA (0.38) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL5117052 | 0.78 | HDAC1 (0.56) | HDAC1HDAC8HDAC6LMNAGAA | |
| SCHEMBL6975571 | 0.78 | HDAC1 (0.49) | HDAC1HDAC8HDAC6LMNAGAA | |
| SCHEMBL2225496 | 0.77 | HDAC1 (0.47) | HDAC1HDAC8HDAC6LMNATSHR | |
| SCHEMBL3060561 | 0.76 | FFAR1 (0.50) | LMNA | |
| SCHEMBL3071306 | 0.76 | FFAR1 (0.50) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL6971887 | 0.76 | HDAC1 (0.56) | HDAC1HDAC8HDAC6LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206457-B1 | BIARYL-OXA(THIA)ZOLE DERIVATIVES AND THEIR USE AS PPARS MODULATORS | LILLY CO ELI (US) | 2003-10-15 | — | — | EP | claimed |