Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029562 | 0.90 | LMNA (0.42) | LMNATSHRGAAKMT2AHPGD | |
| SCHEMBL10029601 | 0.89 | LMNA (0.36) | LMNA | |
| SCHEMBL10029574 | 0.84 | LMNA (0.46) | LMNATSHRGAAKMT2AHPGD | |
| SCHEMBL10029570 | 0.82 | PPARA (0.43) | HPGD | |
| SCHEMBL629104 | 0.81 | S1PR1 (0.43) | LMNATSHRGAAKMT2A | |
| SCHEMBL24883415 | 0.80 | PPARA (0.52) | LMNATSHRGAAHPGD | |
| SCHEMBL6971893 | 0.79 | HDAC1 (0.54) | LMNATSHRGAAKMT2AHPGD | |
| SCHEMBL10029556 | 0.75 | LMNA (0.40) | LMNA | |
| SCHEMBL10029585 | 0.75 | LMNA (0.43) | LMNATSHRGAAKMT2AHPGD | |
| SCHEMBL4415483 | 0.73 | LMNA (0.58) | LMNATSHRGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077854-A1 | COMPOSITIONS AND METHODS FOR MODULATING RETINOL BINDING TO RETINOL BINDING PROTEIN 4 (RBP4) | IRM LLC (BM) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077854-A1 | COMPOSITIONS AND METHODS FOR MODULATING RETINOL BINDING TO RETINOL BINDING PROTEIN 4 (RBP4) | RBP4, RBP1, FABP4 | LMNA 1913/4885TSHR 653/4885GAA 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.