Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703067 | 0.75 | ICAM1 (0.47) | CYP3A4ICAM1SELEVCAM1GAA | |
| Hydrochloric Acid SCHEMBL5010437 | 0.73 | ICAM1 (0.46) | CYP3A4ICAM1SELEVCAM1GAA | |
| SCHEMBL17870827 | 0.72 | CA1 (0.50) | CYP3A4ALDH1A1ICAM1SELEVCAM1 | |
| Chlorthiamid SCHEMBL8541243 | 0.72 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAPKM | |
| SCHEMBL2031170 | 0.72 | ALDH1A1 (0.43) | CYP3A4ALDH1A1L3MBTL1GAAPLAU | |
| Chlorthiamid SCHEMBL54987 | 0.72 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAPKM | |
| SCHEMBL4944903 | 0.69 | POLB (0.38) | CYP3A4ALDH1A1CDK2ICAM1SELE | |
| SCHEMBL23517238 | 0.67 | ADRB2 (0.34) | CYP3A4GAAADRB2 | |
| SCHEMBL1666884 | 0.67 | ALDH1A1 (0.54) | CYP3A4ALDH1A1ICAM1SELEVCAM1 | |
| SCHEMBL111872 | 0.67 | HCAR2 (0.46) | CYP3A4ALDH1A1ICAM1SELEVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6417187-B2 | PALLADIUM CATALYZED ARYLATION, ALKYLATION, DEIODINATION OR DEBROMINATION | DOW AGROSCIENCES LLC | 2002-07-09 | — | — | US | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| US-20020019370-A1 | Palladium catalyzed arylation, alkylation, deiodination or debromination | DOW AGROSCIENCES LLC | 2002-02-14 | — | — | US | disclosed |
| EP-1123287-A1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024735-A1 | INSECTICIDAL 1-(SUBSTITUTED PYRIDYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019370-A1 | Palladium catalyzed arylation, alkylation, deiodination or debromination | DDT, TYR, DDC | CYP3A4 49/4885ALDH1A1 792/4885L3MBTL1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.