Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 11/20 | 0.38 |
| ▸ | F10 | P00742 | 8/20 | 0.37 |
| ▸ | PLG | P00747 | 7/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964921 | 0.90 | F2 (0.41) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL6093307 | 0.80 | ST14 (0.39) | F2F10PLG | |
| SCHEMBL6094675 | 0.71 | MAP4K4 (0.46) | F2 | |
| SCHEMBL6093293 | 0.69 | F2 (0.46) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL6092574 | 0.69 | XIAP (0.44) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL6094023 | 0.68 | F2 (0.52) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL6219378 | 0.68 | F2 (0.52) | F2TMPRSS11DF10PLGPRSS1 | |
| SCHEMBL6093799 | 0.66 | SCN4A (0.54) | F2TMPRSS11DF10PLG | |
| SCHEMBL10478603 | 0.66 | ITGB3 (0.57) | F2TMPRSS11DPLGITGB3ITGA2B | |
| SCHEMBL7586431 | 0.66 | F2 (0.69) | F2TMPRSS11DF10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-A2 | THROMBIN INHIBITORS | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001085760-A1 | THROMBIN INHIBITORS | LEK PHARMACEUTICAL & CHEMICAL CO. DD (SI) | 2001-11-15 | — | — | WO | disclosed |