Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 11/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093307 | 0.90 | ST14 (0.39) | F2ST14 | |
| SCHEMBL6964921 | 0.81 | F2 (0.41) | MAP4K4F2 | |
| SCHEMBL6093293 | 0.72 | F2 (0.46) | F2 | |
| SCHEMBL6971958 | 0.71 | F2 (0.42) | F2 | |
| SCHEMBL6092021 | 0.69 | TSHR (0.62) | — | |
| SCHEMBL4971281 | 0.68 | MAP4K4 (0.51) | MAP4K4 | |
| SCHEMBL6093993 | 0.67 | MAP4K4 (0.53) | MAP4K4 | |
| SCHEMBL10059228 | 0.65 | LTA4H (0.48) | F2 | |
| Hydrochloric Acid SCHEMBL6092077 | 0.65 | MAP4K4 (0.58) | MAP4K4 | |
| SCHEMBL7586431 | 0.64 | F2 (0.69) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191139-A1 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA (SI) | 2003-10-09 | — | — | US | claimed |
| US-7112590-B2 | Thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2006-09-26 | — | — | US | disclosed |
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | disclosed |
| US-20030191139-A1 | Thrombin inhibitors | UNIVERSITY OF LJUBLJANA (SI) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191139-A1 | Thrombin inhibitors | TFPI, F2, SERPINC1 | MAP4K4 2312/4885F2 2/4885ST14 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.