Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969828 | 0.80 | TP53 (0.36) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL6971332 | 0.68 | SCD (0.33) | TSHRHPGDSMN1; SMN2 | |
| SCHEMBL14946484 | 0.67 | TP53 (0.41) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL13825394 | 0.66 | HSD17B10 (0.48) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL2096104 | 0.65 | ALDH1A1 (0.50) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL2109561 | 0.65 | HSD17B10 (0.44) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL8635719 | 0.65 | ALDH1A1 (0.53) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL3823759 | 0.65 | HSD17B10 (0.44) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL1272050 | 0.64 | HSD17B10 (0.41) | TP53ALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL6965560 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |