Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575797 | 0.75 | CCR3 (0.53) | HTR2ACYP2D6 | |
| SCHEMBL6333210 | 0.75 | CCR3 (0.53) | HTR2ACYP2D6 | |
| SCHEMBL6972028 | 0.73 | MAOB (0.64) | SCN5AHTR2ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27358861 | 0.71 | BCHE (0.41) | SCN5AHTR2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL16269909 | 0.71 | SLC6A2 (0.41) | CHRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL12473621 | 0.71 | SLC6A2 (0.41) | CHRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL19844833 | 0.70 | KAT2B (0.48) | ACHECYP2D6 | |
| SCHEMBL19844815 | 0.70 | KAT2B (0.48) | ACHECYP2D6 | |
| SCHEMBL19844838 | 0.70 | KAT2B (0.48) | ACHECYP2D6 | |
| SCHEMBL9703008 | 0.70 | MEN1 (0.49) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294690-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001098270-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |