Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 14/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333210 | 1.00 | CCR3 (0.53) | CCR3CYP2D6HTR2ACARM1PRMT6 | |
| SCHEMBL6972028 | 0.87 | MAOB (0.64) | CCR3CYP2D6HTR2AMAOB | |
| SCHEMBL6217711 | 0.83 | PRMT3 (0.59) | CCR3CARM1PRMT6 | |
| SCHEMBL9703008 | 0.81 | MEN1 (0.49) | MAOB | |
| SCHEMBL7247710 | 0.80 | CARM1 (0.61) | CCR3CARM1PRMT6MAOB | |
| Hydrochloric Acid SCHEMBL9555682 | 0.80 | MEN1 (0.48) | MAOB | |
| Bromide SCHEMBL7249132 | 0.79 | CARM1 (0.60) | CCR3CARM1PRMT6MAOB | |
| SCHEMBL21216506 | 0.78 | CYP2D6 (0.47) | CCR3CYP2D6CARM1PRMT6MAOB | |
| SCHEMBL12090432 | 0.78 | CYP2D6 (0.47) | CCR3CYP2D6CARM1PRMT6MAOB | |
| SCHEMBL6986640 | 0.78 | CYP2D6 (0.47) | CCR3CYP2D6CARM1PRMT6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161240-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1161240-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000035452-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |