Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575797 | 0.87 | CCR3 (0.53) | MAOBHTR2ACYP2D6CCR3 | |
| SCHEMBL6333210 | 0.87 | CCR3 (0.53) | MAOBHTR2ACYP2D6CCR3 | |
| SCHEMBL6311179 | 0.81 | MAOB (0.55) | MAOBMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL9703008 | 0.79 | MEN1 (0.49) | MAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9555682 | 0.78 | MEN1 (0.48) | MAOBMEN1KMT2A | |
| SCHEMBL6972033 | 0.73 | SCN5A (0.41) | SLC6A2SLC6A4SLC6A3SCN5AHTR2A | |
| SCHEMBL7247710 | 0.73 | CARM1 (0.61) | MAOBSLC6A2SLC6A4SLC6A3CCR3 | |
| SCHEMBL6217711 | 0.72 | PRMT3 (0.59) | CCR3 | |
| SCHEMBL3600048 | 0.72 | MAOB (0.48) | MAOBMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8325440 | 0.72 | MAOB (0.51) | MAOBMEN1KMT2AGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294690-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001098270-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |