Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9555682 | 0.99 | MEN1 (0.48) | MEN1KMT2ALMNAHTTHRH3 | |
| SCHEMBL9555723 | 0.87 | HRH3 (0.48) | HRH3 | |
| SCHEMBL9527998 | 0.86 | MEN1 (0.51) | MEN1KMT2ALMNAHTTHRH3 | |
| Oxalic Acid SCHEMBL9528825 | 0.82 | KDM4E (0.53) | LMNAHTTHRH3MAOBACHE | |
| SCHEMBL6333210 | 0.81 | CCR3 (0.53) | MAOB | |
| SCHEMBL7575797 | 0.81 | CCR3 (0.53) | MAOB | |
| Hydrochloric Acid SCHEMBL9556016 | 0.81 | MAOA (0.46) | MEN1KMT2ALMNAHTTMAOB | |
| SCHEMBL7953492 | 0.80 | MAOA (0.53) | MAOBMAOADRD2DRD4 | |
| SCHEMBL9372865 | 0.79 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL6972028 | 0.79 | MAOB (0.64) | MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480794-A1 | 2-Aminopyrimidine-4-carboxamide derivatives, their preparation and therapeutic use | SYNTHELABO (FR) | 1992-04-15 | — | — | EP | disclosed |