Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693161 | 0.77 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL108180 | 0.75 | CASR (0.58) | CASRTNFNOD1 | |
| SCHEMBL16912957 | 0.74 | CASR (0.40) | CASR | |
| SCHEMBL6092113 | 0.73 | KMT2A (0.37) | — | |
| SCHEMBL3391407 | 0.73 | RAB9A (0.43) | — | |
| SCHEMBL18230244 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL18230453 | 0.73 | HTT (0.47) | — | |
| SCHEMBL6967203 | 0.73 | NPC1 (0.53) | — | |
| SCHEMBL18230188 | 0.73 | LDHA (0.41) | — | |
| SCHEMBL2705764 | 0.71 | RAB9A (0.45) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |