Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965425 | 0.98 | EPHX2 (0.42) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL6963975 | 0.92 | SMN1; SMN2 (0.41) | EPHX2PKMNAAAEPHX1ALDH1A1 | |
| SCHEMBL6960166 | 0.84 | NAAA (0.43) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL6957948 | 0.83 | NAAA (0.36) | EPHX2PKMNAAAEPHX1ALDH1A1 | |
| SCHEMBL6963558 | 0.82 | NAAA (0.41) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL23532347 | 0.79 | KCNH2 (0.45) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL16210120 | 0.79 | KCNH2 (0.45) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL9666748 | 0.79 | KCNH2 (0.45) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL9645735 | 0.79 | KCNH2 (0.45) | EPHX2PKMNAAAKCNH2EPHX1 | |
| SCHEMBL9666446 | 0.79 | KCNH2 (0.45) | EPHX2PKMNAAAKCNH2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |