Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965425 | 0.94 | EPHX2 (0.42) | SMN1; SMN2EPHX2PKMNAAACES2 | |
| SCHEMBL6972289 | 0.92 | EPHX2 (0.44) | SMN1; SMN2EPHX2PKMNAAACES2 | |
| SCHEMBL6957948 | 0.86 | NAAA (0.36) | SMN1; SMN2EPHX2PKMNAAATSHR | |
| SCHEMBL599107 | 0.83 | NAAA (0.38) | SMN1; SMN2EPHX2NAAATSHRCES2 | |
| SCHEMBL3886636 | 0.77 | TSHR (0.38) | SMN1; SMN2NAAATSHRCES2CES1 | |
| SCHEMBL27604670 | 0.77 | TSHR (0.38) | SMN1; SMN2NAAATSHRCES2CES1 | |
| SCHEMBL6963558 | 0.77 | NAAA (0.41) | EPHX2PKMNAAACES2CES1 | |
| SCHEMBL2483998 | 0.77 | TP53 (0.38) | SMN1; SMN2TSHRCES2CES1ALDH1A1 | |
| SCHEMBL1989760 | 0.76 | LTA4H (0.35) | SMN1; SMN2NAAATSHRCES2CES1 | |
| SCHEMBL5801979 | 0.76 | NR1H2 (0.53) | NAAATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |