SCHEMBL6972291

SCHEMBL6972291

CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COS(C)(=O)=O)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 10/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6975522 0.81 BDKRB2 (0.50) BDKRB2
SCHEMBL6972695 0.80 BDKRB2 (0.64) BDKRB2
SCHEMBL6972693 0.80 BDKRB2 (0.64) BDKRB2
SCHEMBL6964596 0.76 GAA (0.40) BDKRB2
Phthalimide SCHEMBL6968805 0.75 FSCN1 (0.34) BDKRB2
SCHEMBL6975133 0.75 BDKRB2 (0.51) BDKRB2
SCHEMBL7743013 0.72 BDKRB2 (0.77) BDKRB2
SCHEMBL7746927 0.71 BDKRB2 (0.59) BDKRB2
SCHEMBL7747838 0.71 BDKRB2 (0.71) BDKRB2
SCHEMBL7748415 0.71 BDKRB2 (0.76) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900203-B1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO (JP) 2003-03-19 EP disclosed
US-6083959-A BRADYKININ ANTAGONISTS; FOR THE PREVENTION AND/OR THE TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-04 US disclosed
EP-0900203-A1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP disclosed
WO-1997041104-A1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-06 WO disclosed