Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641466 | 0.87 | GABRP (0.41) | BDKRB2 | |
| SCHEMBL6642298 | 0.84 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL6642301 | 0.84 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL6643340 | 0.82 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL6645021 | 0.81 | MEN1 (0.40) | BDKRB2 | |
| SCHEMBL8014989 | 0.80 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8014987 | 0.80 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8803422 | 0.76 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL6975522 | 0.75 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL7005740 | 0.74 | BDKRB2 (0.41) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900203-B1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6083959-A | BRADYKININ ANTAGONISTS; FOR THE PREVENTION AND/OR THE TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0900203-A1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041104-A1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |